Slide 2: Today we have bigger houses and smaller families more conveniences , buT less Time
Slide 3: we have more degrees, buT less common sense more knowledge , buT less judgmenT
Slide 4: we have more experTs, buT more problems more medicine, buT less wellness
Slide 5: we spend Too recklessly laugh Too liTTle drive Too fasT geT To angry Too quickly sTay up Too laTe read Too liTTle waTch Tv Too much and pray Too seldom
Slide 6: we mulTiplied our possessions, buT reduce our values we Talk Too much, love Too liTTle and lie Too ofTen
Slide 7: we’ve learned how To make living, buT noT a life we’ve added years To life, noT life To years
Slide 8: we have Taller buildings, buT shorTer Tempers wider freeways, buT narrower viewpoinTs we spend more, buT have less we buy more, enjoy iT less we’ve been all The way To The moon and back buT have Trouble crossing The sTreeT To meeT our neighbors. we’ve conquered ouTer space, buT noT inner space we’ve spliT The aTom buT noT our prejudice
Slide 9: we wriTe more, learn less, ———————- plan more, buT accomplish less we’ve learn To rush, buT noT To waiT, we have higher incomes , buT lower morals we build more compuTers To hold more informaTion, To produce more copies buT have less communicaTions we are long on quanTiTy, buT less in qualiTy These are The Time of fasT foods and slow digesTion Tall men , and shorT characTer
Slide 10: more leisure and less fun ,,,,,more kinds of foods ,,,,, buT less nuTriTion Two incomes ,,,,,buT more divorce fancier houses ,,,, buT broken homes
Slide 11: ThaT’s why i propose , ThaT as of Today , you do noT keep anyThing for special occasion , because every day you live is a special occasion. search for knowledge , read more , siT on your fronT porch and admire The view wiThouT paying aTTenTion To your needs. spend more Time wiTh your family and friends , eaT your favoriTe foods, and visiT The places you love .
Slide 12: life is a chain of momenT of enjoymenT, noT only abouT survival. use your crysTal gobleTs, do noT save your besT perfume, and use iT every Time you feel you wanT iT.
Slide 13: remove from vocabulary phrases like “ one of These days “ and “ someday” leT’s wriTe ThaT leTTer we ThoughT of wriTing “ one of These days “ leT’s Tell our families and friends how much we love Them. do noT delay anyThing ThaT adds laughTer and joy To your life . every day , every hour , and every minuTe is special. and you don’T know if iT will be your lasT .
Slide 14: if you’re Too busy To Take The Time To send This message To someone you love , and you Tell yourself you will send iT “ one of These days “ so believe me “ one of these days “ you may noT be here To send iT
Slide 1: The strength of all elements It is seldom that I send out this type of presentation but I found this one particularly impacting and thought provoking. NO you will not have to send it out to 2,5, or even 10 people for luck, just sit back and enjoy the true meaning! Your Friend
Slide 2: The one who takes your hand but touches your heart is a true Friend
Slide 3: We seldom think of what we have, but always think of what we miss
Slide 4: Don ‘ t cry because it ‘ s over now, laugh because it happened
Slide 5: The more precisely you plan, the harder destiny will hit you
Slide 6: What happens, happens for a reason
Slide 7: Don’t make an effort because the best things happen, when you least expect them
Slide 8: The greatest events aren’t the loudest, but the most quiet hours
Slide 9: The most difficult lesson to learn is: Which bridge in life to use or which one to break off
Slide 10: Everybody sees how you seem, however, only some know who you are
Slide 11: He who would like to have something he never had, will have to do something well, that he hasn’t done yet
Slide 12: Perhaps God would want you to become acquainted with many different people in the course of your life, so that when you meet the right ones, you can appreciate and be grateful for them
Slide 13: Plan for tomorrow but LIVE for today
Slide 14: Love doesn’t require two people look at each other, but that they look together in the same direction. (Antoine de Saint Exupery)
Slide 15: Life is drawing without an eraser
Slide 16: I wish you always: Air to breath, Fire to warm you, Water to drink and The earth to live in. I hope you enjoyed it and have a great DAY !
A commonly used blood-pressure drug may prevent the onset of Parkinson’s disease, according to a new study in mice.
Human trials of isradipine (or DynaCirc) – which is prescribed for hypertension and stroke – are now planned.
Over time, Parkinson’s patients lose a set of brain cells that produce the crucial signalling chemical dopamine – and these cells do not regenerate. Without enough dopamine, people cannot control their body movements and ultimately develop severe neurological problems, including dementia.
Scientists have struggled to understand why the dopamine-producing brain cells start dying, but ageing plays a strong role.
Calcium switch
James Surmeier at Northwestern University in Illinois, US, and colleagues found that in young mice these cells use sodium channels to send signals, but in older mice they rely more on a certain kind of calcium channel.
This can prove deadly for a neuron because calcium accumulates inside the cell, eventually triggering a complete breakdown.
Surmeier wondered whether he could reverse the switch to calcium channels: “The cells had put their old childhood tools in the closet. The question was, if we stopped them from behaving like adults, would they go into the closet and get them out again?”
He believed that isradipine, which blocks the same type of calcium channel, could help these cells revert to a younger state. His experiments in a lab dish showed that exposing cells to the drug caused them to increase their use of sodium-based signalling.
Isradipine success
The team then implanted a time-release capsule of the drug beneath the skin of mice that had just reached adulthood. This implant released a daily dose of isradipine that, if scaled up for humans, would correspond to roughly 10 times the dose for a person with hypertension, but less than the amount given to treat stroke.
A week after starting this regimen, the mice also began receiving bi-weekly injections of a chemical called MPTP that poisons the brain’s dopamine-producing cells. The death of these cells simulates Parkinson’s in mice.
Five weeks later, the mice receiving isradipine showed no outward signs of disease. “They looked perfectly normal,” Surmeier says. When researchers tested the animals’ ability to grip a wire mesh, the mice held on just as well as their control counterparts that had not received MPTP.
By comparison, the mice that received MPTP but not isradipine fumbled around showing symptoms of Parkinson’s. “They didn’t move very readily and had to spread their feet out when they walk for extra balance,” says Surmeier.
His team plans to see whether isradipine can help mice that have already developed Parkinson’s disease symptoms.
Trials planned
Epidemiological evidence supports Surmeier’s findings. A survey of people taking isradipine for hypertension found that they had a 30% to 50% reduced risk of Parkinson’s disease, he says.
His team has already recruited a small group of Parkinson’s patients to see if they can tolerate high doses of isradipine, which can cause side-effects such as headaches and dizziness. They are also hoping to conduct a larger trial of the drug to find out if it can significantly slow the disease’s progression.
“There are a lot of different approaches [to developing a cure], and it’s important that they all be tried,” says Linda Herman, a New York-based patient-advocate and member of the Parkinson’s Pipeline Project.
But Herman cautions that people should reserve their enthusiasm for isradipine until researchers show the drug has an effect on Parkinson’s in humans.
Many patients with Parkinson’s currently take a drug called L-dopa, which gets converted to dopamine in the brain. But patients become less responsive to the drug over time and their symptoms worsen.
In severe cases or facing patients that are struggling to breathe, the current medical approach is to deliver pure oxygen and see if the patient’s health condition improves.
But increasing evidence points out that inhaling pure oxygen can actually damage the brain. A new UCLA research examined what is happening during oxygen therapy by brain-imaging. “For decades, the medical community has championed 100 % oxygen as the gold standard for resuscitation. But no one has reported what happens inside our brains when we inhale pure oxygen,” explained Ronald Harper, distinguished professor of neurobiology at the David Geffen School of Medicine at UCLA.
Harper’s team used functional magnetic resonance imaging (fMRI) to get detailed pictures of what happens inside the human brain during two different breathing cases. Increased blood flow determined by the turn on of different brain areas makes them glow on the image.
14 healthy children, aged 8 – 15, had to inhale 100 % oxygen, while their breathing and heart rates were recorded. After 8 minutes, when the children’ respiration returned to normal, the team had them breathe a gas mix made of 5 % carbon dioxide and 95 % oxygen.
Scans in the two situations were analyzed.
“When the children inhaled pure oxygen, their breathing quickened, resulting in the rapid exhalation of carbon dioxide from their bodies. The drop in carbon dioxide narrowed their blood vessels, preventing oxygen from reaching tissue in the brain and heart”, said coauthor Paul Macey, associate researcher in neurobiology.
On the scans, 3 brain areas suddenly heated up: the hippocampus (controlling blood pressure); the cingulate cortex (controlling pain perception and blood pressure); and the insula, which assesses physical and emotional stress.
The intense activity turned on the hypothalamus, involved in regulating the heart rate and hormonal outflow. “Several brain areas responded to 100 % oxygen by kicking the hypothalamus into overdrive. The hypothalamus overreacted by dumping a massive flood of hormones and neurotransmitters into the bloodstream. These chemicals interfere with the heart’s ability to pump blood and deliver oxygen – the opposite effect you want when you’re trying to resuscitate someone”, Harper explained.
The carbon dioxide-oxygen mix did not trigger the hypothalamus’ turn on. “Adding carbon dioxide to the oxygen relaxed the blood vessels, allowed oxygen to reach the heart and brain, calmed the hypothalamus and slowed the release of dangerous chemicals. Pure oxygen kindles the match that fuels a forest fire of harm to the body,” said Harper. “But a little whiff of carbon dioxide makes it all go away”, Macey added.
The finding strongly points to the addition of carbon dioxide to oxygen therapy, especially for resuscitation, oxygen administration for over a few minutes, stroke, heart attack, carbon monoxide poisoning and other long-term oxygen therapies.
Many European hospitals already resuscitate patients with room air (a mix of nitrogen, oxygen and carbon dioxide) or oxygen and carbon dioxide mixes.
Sri Sri: Whom do you call a successful person? What are the signs of success? Blood Pressure? Fear? Ego? Anxiety? Are these the signs of success? Then what are the signs? Power?
Sri Sri Ravi Shankar Answer: Look at all the people who are in power, there is such a struggle and they are not happy. Then when they have power, there is so much fear that they may lose it! To maintain it, again there is struggle and when they have lost it the memory of that power makes them miserable… A smile that comes from the depth of an innocent heart, the freedom which you are able to feel in life.. these are the signs of success.
Are you free? Then you are successful!
Are you in the present moment? Then you are successful!
Are you useful to the people around you? Then your life is a success!
Do you feel love for all humanity?
Then that is a sign of success in Life!
I fantasize about writing a book called The Happiness Formula. The idea would be to create a simple formula for troubleshooting your life and improving your happiness. On page one would be this top formula.
Happiness = health + money + social life + meaning
The rest of the book would be nested formulas that further explain each component of happiness. For example…
Health = sleep + diet + exercise
And then down another level…
Sleep = schedule + technique
And down another level until it starts getting practical…
Sleep Technique = consistent bedtime and waking time + no reading or TV in bed + no booze or caffeine…
And so on.
To make the Happiness Formulas extra useful, the highest priorities would appear first (leftmost) in the formula. For example, in the top Happiness Formula (Happiness = health + money + social life + meaning), health is a higher priority than money, which is a higher priority than social life, etc.
I realize you’ll argue with my ranking of priorities and point out all the exceptions. For example, if you have no money, you can’t afford to be healthy. But the formula only shows priorities, not absolutes. Obviously you always need a source of money, but the priority list shows that you shouldn’t take a job with high pay that will significantly affect your health. It makes more sense to get healthy and then leverage your health to get the best job. (Healthy looking people land better jobs and are more highly paid. Their brains work better too, and they have more energy.)
I rank money higher than social life or meaning because once you have money, those other things are easier to get. For example, you won’t have much of a social life if you can’t afford to do anything. And you can’t make money if your health is a mess.
You might wonder how something like “money” can be broken down into a formula so easily that someone could just follow it to get more. I think it can be done.
Money = Income + investments
Investments = (See my 9-point investment plan below that has been endorsed by economists.)
Scott’s 9-Point Investment Plan
Do these steps in the order shown…
1. Make a will
2. Pay off your credit cards
3. Get term life insurance if you have a family to support
4. Fund your 401k to the maximum
5. Fund your IRA to the maximum
6. Buy a house if you want to live in a house and can afford it
7. Put six months worth of expenses in a money-market account
8. Take whatever money is left over and invest 70% in a stock index fund and 30% in a bond fund through any discount broker and never touch it until retirement
9. If any of this confuses you, or you have something special going on (retirement, college planning, tax issues), hire a fee-based financial planner, not one who charges a percentage of your portfolio
Part of the reason I don’t turn The Happiness Formula into a book is that it would only be about 20 pages long. Its power is in its brevity, and brevity is not rewarded in our economy. If the best book in the world was only 20 pages long, no one would buy it. They’d stand in Borders and read it cover to cover.
So I won’t be writing that book. Maybe it needs to be a wiki project.
